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CS-W001157 4
Total: USD 88.00

3-Aminopyrazine-2-carbaldehyde

  • CAS No. 32710-14-8

  • Cat. No. CS-W021844
  • Purity≥97%
  • MDL No.MFCD10696886

*For research and further manufacturing use only, not for direct human use.

3-Aminopyrazine-2-carbaldehyde|CS-W021844

Structure of 32710-14-8

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General Information

  • CAS No. 32710-14-8
  • Cat. No. CS-W021844
  • Purity ≥97%
  • MDL No. MFCD10696886
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₅N₃O
  • Molecular Weight 123.11
  • Synonym(s) 2-Pyrazinecarboxaldehyde,3-amino-
  • SMILES NC1=NC=CN=C1C=O

Description

3-Aminopyrazine-2-carbaldehyde features a pyrazine core functionalized with an amino group at the 3-position and a formyl group at the 2-position, enabling direct incorporation into heterocyclic scaffolds. This bifunctional motif supports efficient coupling reactions and serves as a key building block in medicinal chemistry and catalyst design.

Application

3-Aminopyrazine-2-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling direct incorporation of both amino and aldehyde functionalities into complex scaffolds. Its orthogonal reactivity facilitates sequential transformations in medicinal chemistry and materials science, while its bench stability supports reliable handling in standard synthetic workflows.

Synthesis

  • Route1

    References

    • SMITHKLINE BEECHAM CORPORATION Patent: WO2006/63167 A1, 2006 ; Location in patent: Page/Page column 70-71 ; WO 2006/063167 A1
  • Route2
    • null|null
      174198-30-2
    • ~28%
    • In-stock
      3-Aminopyrazine-2-carbaldehyde|CS-W021844
      32710-14-8

    References

    • Okawa, Tomohiro; Eguchi, Shoji Tetrahedron, 1998 , vol. 54, # 22 p. 5853 - 5868
  • Route3

    References

    • Journal of Molecular Structure, , vol. 741, # 1-3 p. 67 - 75

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   68.87
  • LogP   -0.1287
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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