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CS-W001157 4
Total: USD 88.00

NSC 123649

  • CAS No. 16298-03-6

  • Cat. No. CS-D1517
  • Purity≥98%
  • MDL No.MFCD00010097

*For research and further manufacturing use only, not for direct human use.

NSC 123649|CS-D1517

Structure of 16298-03-6

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General Information

  • CAS No. 16298-03-6
  • Cat. No. CS-D1517
  • Purity ≥98%
  • MDL No. MFCD00010097
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₇N₃O₂
  • Molecular Weight 153.14
  • Synonym(s) Methyl 3-aminopyrazine-2-carboxylate; Methyl 3-aminopyrazinecarboxylate; Methyl 3-aminopyrazine-2-carboxylic ester
  • SMILES O=C(C1=NC=CN=C1N)OC

Description

Methyl 3-amino-2-pyrazinecarboxylate has been used in: synthesis of 2-arylpteridin-4-ones and piperazine-derived 2-furan-2-yl-[1,2,4]triazolo[1,5-a] pyrazinesreactions with isocyanates and aroyl chlorides for conversion to pteridinediones

Synthesis

  • Route1
    • null|null
      67-56-1
    • In-stock
      3-Amino-2-pyrazinecarboxylic acid|CS-W020071
      5424-01-1
    • ~77%
    • In-stock
      NSC 123649|CS-D1517
      16298-03-6

    References

    • Forns, Pilar; Esteve, Cristina; Taboada, Lorena; Alonso, Juan Antonio; Orellana, Adelina; Maldonado, Monica; Carreno, Cristina; Ramis, Isabel; Lopez, Manel; Miralpeix, Montserrat; Vidal, Bernat Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 8 p. 2784 - 2788
  • Route2

    References

    • American Cyanamid Company Patent: US5252538 A1, 1993 ;
  • Route3

    References

    • Vontor, Tomas; Palat, Karel; Lycka, Antonin Collection of Czechoslovak Chemical Communications, 1989 , vol. 54, # 5 p. 1306 - 1310

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   78.1
  • LogP   -0.1546
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   1

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