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*For research and further manufacturing use only, not for direct human use.
Structure of 32222-45-0
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This chiral building block features a (R)-configured stereocenter flanked by a hydroxyl group and a 4-fluorophenyl moiety, delivering enhanced metabolic stability. The electron-withdrawing fluorine substituent imparts unique polarity and directional reactivity, enabling selective functionalization in asymmetric synthesis. Bench-stable and moisture-tolerant, it integrates seamlessly into complex molecular architectures for pharmaceutical development.
(R)-2-(4-Fluorophenyl)-2-hydroxyacetic acid serves as a valuable chiral building block in the synthesis of pharmaceutical intermediates, particularly for CNS-targeted agents. Its well-defined stereochemistry and hydroxyl functionality enable reliable derivatization via esterification, amidation, or oxidation. The molecule exhibits good bench stability and facilitates efficient purification, making it suitable for scale-up in medicinal chemistry campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: