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CS-W001157 4
Total: USD 88.00

2-(4-Fluorophenyl)-2-methoxyacetic acid

  • CAS No. 2340-00-3

  • Cat. No. CS-0532572
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(4-Fluorophenyl)-2-methoxyacetic acid|CS-0532572

Structure of 2340-00-3

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General Information

  • CAS No. 2340-00-3
  • Cat. No. CS-0532572
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₉FO₃
  • Molecular Weight 184.16
  • Synonym(s) None
  • SMILES O=C(C(C1=CC=C(C=C1)F)OC)O

Description

This boronate moiety integrates a 4-fluorophenyl group and a methoxyacetic acid side chain, offering enhanced solubility and stability in polar reaction media. The para-fluoro substitution imparts electron-withdrawing character, facilitating downstream functionalization in cross-coupling processes.

Application

2-(4-Fluorophenyl)-2-methoxyacetic acid serves as a versatile building block for medicinal chemistry and agrochemical synthesis, enabling efficient access to chiral α-aryl-α-hydroxy acid derivatives. Its bench-stable structure features orthogonal functional groups—aromatic fluorine and ester-tethered methoxy—that tolerate standard coupling and transformation conditions. The molecule facilitates direct incorporation into heterocyclic scaffolds and supports late-stage diversification via selective deprotection or conjugate addition pathways.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.53
  • LogP   1.5978
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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