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CS-W001157 4
Total: USD 88.00

Methyl 4-(bromomethyl)picolinate

  • CAS No. 317335-16-3

  • Cat. No. CS-0616843
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 4-(bromomethyl)picolinate|CS-0616843

Structure of 317335-16-3

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General Information

  • CAS No. 317335-16-3
  • Cat. No. CS-0616843
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈BrNO₂
  • Molecular Weight 230.06
  • Synonym(s) None
  • SMILES O=C(C1=NC=CC(CBr)=C1)OC

Description

Methyl 4-(bromomethyl)picolinate features a bromomethyl group at the pyridine ring's 4-position, enabling direct functionalization in cross-coupling and nucleophilic substitution reactions. This bench-stable reagent integrates readily into synthetic sequences requiring selective alkylation or chain extension, particularly in medicinal chemistry and heterocyclic synthesis.

Application

Methyl 4-(bromomethyl)picolinate serves as a versatile building block for constructing bioactive heterocycles and pharmaceutical intermediates. The bromomethyl group enables efficient nucleophilic substitution, facilitating C–C and C–heteroatom bond formation under mild conditions. Its stability under standard bench handling and compatibility with diverse functional groups make it ideal for iterative synthesis workflows in medicinal chemistry and process development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   1.7631
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   2

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