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CS-W001157 4
Total: USD 88.00

m-PEG2-Amine

  • CAS No. 31576-51-9

  • Cat. No. CS-W008429
  • Molecule weight119.16
  • Purity≥98%
  • MDL No.MFCD09032941

*For research and further manufacturing use only, not for direct human use.

m-PEG2-Amine|CS-W008429

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General Information

  • CAS No. 31576-51-9
  • Cat. No. CS-W008429
  • Purity ≥98%
  • MDL No. MFCD09032941
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₃NO₂
  • Molecular Weight 119.16
  • Synonym(s) 2-(2-Methoxyethoxy)Ethanamine
  • SMILES COCCOCCN

Description

m-PEG2-Amine features a short, hydrophilic PEG chain flanked by amine functionality, enabling efficient conjugation in bioconjugation workflows. This bench-stable reagent offers enhanced solubility in aqueous and organic media, simplifying handling in peptide and protein labeling applications.

Application

m-PEG2-Amine serves as a versatile bifunctional linker, enabling efficient conjugation in peptide and protein modification workflows. Its two ethylene glycol units provide enhanced solubility and reduced non-specific binding, while the terminal amine facilitates straightforward coupling reactions with carboxylic acids or activated esters. The molecule exhibits excellent bench stability and is compatible with standard purification methods, making it ideal for use in bioconjugation, drug delivery systems, and solid-phase synthesis applications.

Synthesis

  • Route1

    References

    • Seguer, J.; Selve, C.; Allouch, M.; Infante, M. R. Journal of the American Oil Chemists' Society, 1996 , vol. 73, # 1 p. 79 - 86
  • Route2

    References

    • Clerc, Jerome; Schellenberg, Barbara; Groll, Michael; Bachmann, Andre S.; Huber, Robert; Dudler, Robert; Kaiser, Markus European Journal of Organic Chemistry, 2010 , # 21 p. 3991 - 4003
  • Route3
    • null|null
      179820-15-6
    • ~67%
    • In-stock
      m-PEG2-Amine|CS-W008429
      31576-51-9

    References

    • Harjani, Jitendra R.; Liang, Chen; Jessop, Philip G. Journal of Organic Chemistry, 2011 , vol. 76, # 6 p. 1683 - 1691

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2810
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H227-H301
Precautionary Statements : P210-P264-P270-P280-P330-P370+P378-P403-P405-P501

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   -0.3919
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

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