(S)-1-Boc-Alpha-(Fmoc-Amino)-4-Piperidinebutanoic acid

Name: (S)-1-Boc-Alpha-(Fmoc-Amino)-4-Piperidinebutanoic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 313052-18-5
Cat. No. CS-0439474
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(S)-1-Boc-Alpha-(Fmoc-Amino)-4-Piperidinebutanoic acid|CS-0439474

Structure of 313052-18-5

Size

Price

Quantity

* Please select Quantity before adding items.

Description

(S)-1-Boc-Alpha-(Fmoc-Amino)-4-Piperidinebutanoic acid features a chiral piperidine scaffold with orthogonal protecting groups: a Boc group at the amine and an Fmoc moiety on the alpha position. This bifunctional building block enables seamless incorporation into peptide chains via solid-phase synthesis, where the Fmoc group permits selective deprotection under mild basic conditions, while the Boc-protected amine remains stable. The piperidine ring imparts conformational rigidity, enhancing structural precision in macrocyclic or peptidomimetic architectures. Designed for high compatibility with standard coupling protocols, this intermediate streamlines access to complex bioactive molecules.

Application

(S)-1-Boc-α-(Fmoc-amino)-4-piperidinebutanoic acid serves as a versatile building block for the synthesis of peptidomimetics and bioactive heterocycles. The Boc and Fmoc groups provide orthogonal protection for amine functionalities, enabling sequential coupling in solid-phase and solution-phase syntheses. The piperidinebutanoic acid scaffold offers structural rigidity and favorable pharmacophore characteristics, facilitating integration into diverse API candidates through standard amide bond formation and cyclization protocols.

General Information

CAS No. 313052-18-5
Cat. No. CS-0439474
Purity ≥98%
MDL No. None
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₉H₃₆N₂O₆
Molecular Weight 508.61
Synonym(s) (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-(1-(tert-butoxycarbonyl)piperidin-4-yl)butanoic acid
SMILES C(OC(N[C@@H](CCC1CCN(C(OC(C)(C)C)=O)CC1)C(O)=O)=O)C2C=3C(C=4C2=CC=CC4)=CC=CC3

Computational Chemistry Data

TPSA 105.17
LogP 5.4056
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 7

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Amino Acids and their Derivatives Alanine and derivatives

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

313052-18-5 sigma313052-18-5 manufacturer313052-18-5 price313052-18-5 structure313052-18-5 SDSbuy 313052-18-5313052-18-5 supplier313052-18-5 uses313052-18-5 molecular weightprice of 313052-18-5313052-18-5 chemical name formula of 313052-18-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(S)-1-Boc-Alpha-(Fmoc-Amino)-4-Piperidinebutanoic acid

CAS No. 313052-18-5

Recommended Products