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CS-W001157 4
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1H-Indazole-7-carbaldehyde

  • CAS No. 312746-72-8

  • Cat. No. CS-0044004
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1H-Indazole-7-carbaldehyde|CS-0044004

Structure of 312746-72-8

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General Information

  • CAS No. 312746-72-8
  • Cat. No. CS-0044004
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₆N₂O
  • Molecular Weight 146.15
  • Synonym(s) 7-Formylindazole
  • SMILES O=CC1=CC=CC2=C1NN=C2

Description

1H-Indazole-7-carbaldehyde features a rigid heteroaromatic core with a strategically positioned aldehyde group, enabling direct incorporation into diverse synthetic scaffolds. This bench-stable compound serves as a key building block for bioactive molecule development, particularly in kinase inhibitor and fluorescent probe design.

Application

1H-Indazole-7-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling direct functionalization at the 7-position via nucleophilic addition or coupling reactions. Its aldehyde functionality offers high reactivity in Ugi-type condensations, reductive amination, and oxime formation, while maintaining bench stability under standard laboratory conditions. The indazole core provides structural rigidity and pharmacophoric relevance, making it suitable for medicinal chemistry campaigns targeting kinase inhibitors and other bioactive scaffolds.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   1.3754
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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