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CS-W001157 4
Total: USD 88.00

1-(1H-Indazol-7-yl)ethan-1-one

  • CAS No. 1159511-22-4

  • Cat. No. CS-0044885
  • Purity≥98%
  • MDL No.MFCD11869765

*For research and further manufacturing use only, not for direct human use.

1-(1H-Indazol-7-yl)ethan-1-one|CS-0044885

Structure of 1159511-22-4

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General Information

  • CAS No. 1159511-22-4
  • Cat. No. CS-0044885
  • Purity ≥98%
  • MDL No. MFCD11869765
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O
  • Molecular Weight 160.17
  • Synonym(s) 1-(1H-indazol-7-yl)ethanone
  • SMILES CC(C1=CC=CC2=C1NN=C2)=O

Description

1-(1H-Indazol-7-yl)ethan-1-one features a fused bicyclic indazolyl core paired with a ketone-functionalized ethyl side chain, enabling direct integration into heterocyclic scaffolds. This bench-stable building block supports rapid diversification in medicinal chemistry campaigns targeting kinase inhibition and CNS-active compounds.

Application

1-(1H-Indazol-7-yl)ethan-1-one serves as a versatile building block for constructing indazole-based scaffolds in medicinal chemistry. Its ketone functionality enables direct nucleophilic addition, reductive amination, or enolate-mediated coupling, facilitating access to diverse analogs. The molecule exhibits good bench stability and compatibility with common functional groups, simplifying purification and integration into multi-step syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   45.75
  • LogP   1.7655
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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