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(S)-2-(tert-Butoxycarbonylamino)succinic acid benzyl ester

  • CAS No. 30925-18-9

  • Cat. No. CS-B1295
  • Purity≥98%
  • MDL No.MFCD00065563

*For research and further manufacturing use only, not for direct human use.

(S)-2-(tert-Butoxycarbonylamino)succinic acid benzyl ester|CS-B1295

Structure of 30925-18-9

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General Information

  • CAS No. 30925-18-9
  • Cat. No. CS-B1295
  • Purity ≥98%
  • MDL No. MFCD00065563
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₂₁NO₆
  • Molecular Weight 323.34
  • Synonym(s) N-(tert-Butoxycarbonyl)aspartic acid 1-benzyl ester; N-(tert-Butoxycarbonyl)aspartic acid benzyl ester
  • SMILES O=C(O)C[C@@H](C(OCC1=CC=CC=C1)=O)NC(OC(C)(C)C)=O

Description

(S)-2-(tert-Butoxycarbonylamino)succinic acid benzyl ester is a chiral building block featuring a protected amino group and a labile ester moiety, enabling sequential deprotection and coupling in peptide synthesis. This bench-stable derivative facilitates the controlled installation of side-chain functionalities in complex oligopeptide architectures.

Synthesis

  • Route1

    References

    • Cantacuzene, D.; Pascal, F.; Guerreiro, C. Tetrahedron, 1987 , vol. 43, # 8 p. 1823 - 1826
  • Route2

    References

    • Chemical communications (Cambridge, England), , # 19 p. 1908 - 1909
  • Route3
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      275827-12-8
    • ~%
    • In-stock
      (S)-2-(tert-Butoxycarbonylamino)succinic acid benzyl ester|CS-B1295
      30925-18-9

    References

    • Synlett, , # 3 p. 400 - 402

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   101.93
  • LogP   2.0978
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   6

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