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CS-W001157 4
Total: USD 88.00

1H-Pyrazol-3-ol

  • CAS No. 60456-92-0

  • Cat. No. CS-0044191
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1H-Pyrazol-3-ol|CS-0044191

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General Information

  • CAS No. 60456-92-0
  • Cat. No. CS-0044191
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃H₄N₂O
  • Molecular Weight 84.08
  • Synonym(s) 5-hydroxy-pyrazole
  • SMILES OC1=NNC=C1

Description

1H-Pyrazol-3-ol delivers a versatile heterocyclic scaffold with enhanced solubility and thermal stability. The phenolic hydroxyl group enables direct functionalization, while the adjacent nitrogen atoms facilitate coordination in catalytic systems. This compound serves as a key building block for bioactive molecules and advanced materials.

Application

1H-Pyrazol-3-ol serves as a versatile building block in medicinal chemistry, enabling the construction of heterocyclic scaffolds through well-established coupling and functionalization reactions. Its phenolic hydroxyl group offers direct handle for derivatization, while the pyrazole core provides structural rigidity and hydrogen-bonding capability. The compound exhibits good bench stability and facilitates efficient purification, making it suitable for high-throughput synthesis and process-scale applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   48.91
  • LogP   0.1153
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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