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CS-W001157 4
Total: USD 88.00

3-(Pyridin-4-yl)propan-1-amine

  • CAS No. 30532-36-6

  • Cat. No. CS-W005333
  • Purity≥98%
  • MDL No.MFCD08234495

*For research and further manufacturing use only, not for direct human use.

3-(Pyridin-4-yl)propan-1-amine|CS-W005333

Structure of 30532-36-6

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General Information

  • CAS No. 30532-36-6
  • Cat. No. CS-W005333
  • Purity ≥98%
  • MDL No. MFCD08234495
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂N₂
  • Molecular Weight 136.19
  • Synonym(s) 4-Pyridylpropylamine
  • SMILES NCCCC1=CC=NC=C1

Description

3-(Pyridin-4-yl)propan-1-amine features a conjugated pyridine ring linked via a flexible propyl chain, enabling precise spatial orientation in molecular scaffolds. This amine integrates readily into functionalized architectures, offering enhanced solubility and directional binding potential in synthetic and medicinal chemistry applications.

Application

3-(Pyridin-4-yl)propan-1-amine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocyclic scaffolds through standard coupling and functionalization reactions. Its pyridyl-alkylamine motif offers favorable solubility, bench stability, and compatibility with common protecting group strategies, facilitating efficient synthesis of targeted compounds. Functions effectively in amide bond formation, reductive amination, and transition-metal-catalyzed transformations.

Synthesis

  • Route1
    • null|null
      84200-08-8
    • ~89%
    • In-stock
      3-(Pyridin-4-yl)propan-1-amine|CS-W005333
      30532-36-6

    References

    • Mayer, Joachim M.; Testa, Bernard Helvetica Chimica Acta, 1982 , vol. 65, # 6 p. 1868 - 1884
  • Route2

    References

    • Subramanyam Tetrahedron Letters, 2000 , vol. 41, # 34 p. 6537 - 6540
  • Route3
    • 3-(Pyridin-4-yl)propanamide|CS-0239032
      84200-07-7
    • ~%
    • In-stock
      3-(Pyridin-4-yl)propan-1-amine|CS-W005333
      30532-36-6

    References

    • US4788206 A1, ; US4927838 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   0.9729
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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