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CS-W001157 4
Total: USD 88.00

3-(3-Pyridyl)propylamine

  • CAS No. 41038-69-1

  • Cat. No. CS-0158399
  • Purity≥97%
  • MDL No.MFCD09886637

*For research and further manufacturing use only, not for direct human use.

3-(3-Pyridyl)propylamine|CS-0158399

Structure of 41038-69-1

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General Information

  • CAS No. 41038-69-1
  • Cat. No. CS-0158399
  • Purity ≥97%
  • MDL No. MFCD09886637
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂N₂
  • Molecular Weight 136.19
  • Synonym(s) 3-(Pyridin-3-yl)propan-1-amine
  • SMILES C(CC1=CN=CC=C1)CN

Description

3-(3-Pyridyl)propylamine features a pyridyl ring linked via a propyl spacer to a primary amine, enabling versatile coordination in catalysis and ligand design. This electron-deficient heteroaromatic scaffold integrates readily into bioactive scaffolds, offering enhanced solubility and stability under standard conditions.

Application

3-(3-Pyridyl)propylamine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through amine-functionalized linker systems. Its pyridyl group provides a handle for metal coordination and hydrogen bonding, while the primary amine facilitates conjugation, derivatization, and salt formation. Bench-stable and compatible with standard coupling reactions, it functions effectively in peptide synthesis and ligand design workflows.

Synthesis

  • Route1
    • (3-Pyridin-3-yl-propyl)-carbamic acid tert-butyl ester|CS-0340091
      859239-24-0
    • ~68%
    • In-stock
      3-(3-Pyridyl)propylamine|CS-0158399
      41038-69-1

    References

    • HUMAN BIOMOLECULAR RESEARCH INSTITUTE Patent: WO2005/66162 A1, 2005 ; Location in patent: Page/Page column 62 ; WO 2005/066162 A1
  • Route2
    • null|null
      84200-00-0
    • ~86%
    • In-stock
      3-(3-Pyridyl)propylamine|CS-0158399
      41038-69-1

    References

    • Mayer, Joachim M.; Testa, Bernard Helvetica Chimica Acta, 1982 , vol. 65, # 6 p. 1868 - 1884
  • Route3

    References

    • Yano, Jason K.; Denton, Travis T.; Cerny, Matthew A.; Zhang, Xiaodong; Johnson, Eric F.; Cashman, John R. Journal of Medicinal Chemistry, 2006 , vol. 49, # 24 p. 6987 - 7001

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   38.91
  • LogP   0.9729
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   3

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