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CS-W001157 4
Total: USD 88.00

1,2-Epoxyoctane

  • CAS No. 2984-50-1

  • Cat. No. CS-0152296
  • Purity≥97%
  • MDL No.MFCD00005157

*For research and further manufacturing use only, not for direct human use.

1,2-Epoxyoctane|CS-0152296

Structure of 2984-50-1

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General Information

  • CAS No. 2984-50-1
  • Cat. No. CS-0152296
  • Purity ≥97%
  • MDL No. MFCD00005157
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₆O
  • Molecular Weight 128.21
  • Synonym(s) 1-Octene epoxide
  • SMILES CCCCCCC1CO1

Description

1,2-Epoxyoctane is a linear epoxide featuring a terminal oxirane ring on an octyl chain. This bench-stable, moisture-tolerant compound serves as a reactive handle for nucleophilic ring-opening transformations. It integrates readily into synthetic sequences requiring controlled functionalization of aliphatic chains, enabling access to diols, ethers, and other oxygenated derivatives under mild conditions.

Application

1,2-Epoxyoctane serves as a versatile epoxide building block in synthetic organic chemistry, enabling stereoselective ring-opening reactions with nucleophiles under mild conditions. Its linear alkyl chain provides favorable solubility and handling characteristics, while the terminal epoxide functionality exhibits predictable reactivity in standard transformations such as acid-catalyzed hydrolysis or aminolysis. This compound functions effectively in the synthesis of diols, amino alcohols, and functionalized intermediates for pharmaceutical and fine chemical applications.

Synthesis

  • Route1
    • null|null
      111-66-0
    • ~97%
    • In-stock
      1,2-Epoxyoctane|CS-0152296
      2984-50-1

    References

    • Sugimoto, Hiroshi; Tung, Hui-Chan; Sawyer, Donald T. Journal of the American Chemical Society, 1988 , vol. 110, # 8 p. 2465 - 2470
  • Route2
    • null|null
      111-66-0
    • ~79%
    • null|null
      111-14-8
    • In-stock
      1,2-Epoxyoctane|CS-0152296
      2984-50-1

    References

    • Carraro, Mauro; Sandei, Luca; Sartorel, Andrea; Scorrano, Gianfranco; Bonchio, Marcella Organic Letters, 2006 , vol. 8, # 17 p. 3671 - 3674
  • Route3

    References

    • Journal of the Chemical Society, Chemical Communications, , # 2 p. 171 - 172

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS07
Signal Word : Warning
UN#: 3271
Class : 3
Packing Group : Ⅲ
Hazard Statements : H226-H315-H319-H335
Precautionary Statements : P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.53
  • LogP   2.3556
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   5

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