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CS-W001157 4
Total: USD 88.00

1,2-Epoxydecane

  • CAS No. 2404-44-6

  • Cat. No. CS-0204736
  • Purity≥97%
  • MDL No.MFCD00005158

*For research and further manufacturing use only, not for direct human use.

1,2-Epoxydecane|CS-0204736

Structure of 2404-44-6

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General Information

  • CAS No. 2404-44-6
  • Cat. No. CS-0204736
  • Purity ≥97%
  • MDL No. MFCD00005158
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀O
  • Molecular Weight 156.27
  • Synonym(s) 2-Octyloxirane
  • SMILES O1CC1CCCCCCCC

Description

1,2-Epoxydecane is a linear, bench-stable epoxide featuring a terminal oxirane ring flanked by a saturated decane chain. This structure enables selective ring-opening reactions under mild conditions, facilitating the introduction of diverse nucleophiles into long-chain frameworks. The molecule integrates seamlessly into synthetic sequences requiring controlled functionalization of aliphatic chains, particularly in polymer modification and fine chemical synthesis.

Application

1,2-Epoxydecane serves as a versatile epoxide building block in synthetic organic chemistry, enabling stereoselective ring-opening reactions with nucleophiles under mild conditions. Its linear alkyl chain provides excellent solubility and bench stability, while the terminal epoxide functionality offers high reactivity toward amines, thiols, and carboxylic acids—facilitating access to functionalized alcohols, amino alcohols, and thioethers. Widely used in the synthesis of chiral intermediates and complex molecular architectures, it functions reliably in standard reaction protocols without requiring specialized handling.

Synthesis

  • Route1
    • null|null
      872-05-9
    • ~94%
    • In-stock
      1,2-Epoxydecane|CS-0204736
      2404-44-6

    References

    • Limnios, Dimitris; Kokotos, Christoforos G. Journal of Organic Chemistry, 2014 , vol. 79, # 10 p. 4270 - 4276
  • Route2
    • 2-(Oct-7-en-1-yl)oxirane|CS-0358861
      85721-25-1
    • ~91%
    • In-stock
      1,2-Epoxydecane|CS-0204736
      2404-44-6

    References

    • Callis, Nuria Miro; Thiery, Emilie; Le Bras, Jean; Muzart, Jacques Tetrahedron Letters, 2007 , vol. 48, # 46 p. 8128 - 8131
  • Route3

    References

    • Robinson, Philip L.; Barry, Carey N.; Kelly, Jeffery W.; Evans, Slayton A. Journal of the American Chemical Society, 1985 , vol. 107, # 18 p. 5210 - 5219

Safety Information

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GHS Pictogram :
GHS No : GHS08,GHS09
Signal Word : Danger
UN#: 3082
Class : 9
Packing Group : Ⅲ
Hazard Statements : H227-H315-H319-H372-H410
Precautionary Statements : P210-P264-P273-P280-P302+P352-P362-P370+P378-P391-P501

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Computational Chemistry Data

  • TPSA   12.53
  • LogP   3.1358
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   7

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