Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Bromo-2-fluoronicotinic acid

  • CAS No. 29241-66-5

  • Cat. No. CS-W003350
  • Purity≥98%
  • MDL No.MFCD06797939

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-fluoronicotinic acid|CS-W003350

Structure of 29241-66-5

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 29241-66-5
  • Cat. No. CS-W003350
  • Purity ≥98%
  • MDL No. MFCD06797939
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₃BrFNO₂
  • Molecular Weight 220.00
  • Synonym(s) 5-bromo-2-fluoropyridine-3-carboxylicaci
  • SMILES BrC(C=N1)=CC(C(O)=O)=C1F

Description

5-Bromo-2-fluoronicotinic acid features a strategically positioned bromine and fluorine substituent on the pyridine ring, enabling direct incorporation into Suzuki-Miyaura cross-coupling and other transition-metal-catalyzed transformations. The electron-deficient heterocycle facilitates efficient functionalization in medicinal chemistry and materials synthesis workflows under standard conditions.

Application

5-Bromo-2-fluoronicotinic acid serves as a versatile building block for the synthesis of biologically active heterocycles and pharmaceutical intermediates. Its dual halogenation enables efficient palladium-catalyzed cross-coupling reactions, while the carboxylic acid functionality supports direct derivatization or activation for amide formation. The compound exhibits excellent bench stability and facilitates orthogonal functional group manipulation in complex molecule assembly.

Synthesis

  • Route1

    References

    • Bristol-Myers Squibb Company Patent: US2007/78140 A1, 2007 ; Location in patent: Page/Page column 36 ; US 20070078140 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   50.19
  • LogP   1.6814
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Bromo-2-fluoronicotinic acid sigma5-Bromo-2-fluoronicotinic acid manufacturer5-Bromo-2-fluoronicotinic acid price5-Bromo-2-fluoronicotinic acid structure5-Bromo-2-fluoronicotinic acid SDSbuy 5-Bromo-2-fluoronicotinic acid5-Bromo-2-fluoronicotinic acid supplier5-Bromo-2-fluoronicotinic acid uses5-Bromo-2-fluoronicotinic acid molecular weightprice of 5-Bromo-2-fluoronicotinic acid5-Bromo-2-fluoronicotinic acid chemical name formula of 5-Bromo-2-fluoronicotinic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label