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CS-W001157 4
Total: USD 88.00

4-Trifluoromethylphenyl hydrazine hydrochloride

  • CAS No. 2923-56-0

  • Cat. No. CS-W020061
  • Purity≥97%
  • MDL No.MFCD00204233

*For research and further manufacturing use only, not for direct human use.

4-Trifluoromethylphenyl hydrazine hydrochloride|CS-W020061

Structure of 2923-56-0

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General Information

  • CAS No. 2923-56-0
  • Cat. No. CS-W020061
  • Purity ≥97%
  • MDL No. MFCD00204233
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₈ClF₃N₂
  • Molecular Weight 212.60
  • Synonym(s) 4-trifluoromethylphenyl hydrazine hydrochlroide
  • SMILES FC(C1=CC=C(NN)C=C1)(F)F.Cl

Description

4-Trifluoromethylphenyl hydrazine hydrochloride delivers a robust, bench-stable platform for constructing heterocyclic scaffolds. The para-trifluoromethyl group enhances electron deficiency and metabolic stability, while the hydrazine moiety enables efficient coupling reactions under mild conditions. This reagent integrates seamlessly into synthetic workflows requiring high functional group tolerance and predictable reactivity.

Application

4-Trifluoromethylphenyl hydrazine hydrochloride serves as a reliable building block for heterocyclic synthesis, enabling efficient access to pyrazoles and triazoles via cycloaddition reactions. Its bench-stable form facilitates handling and purification, while the electron-withdrawing trifluoromethyl group enhances electrophilic reactivity in coupling processes. Functions effectively in standard azo-coupling and cyclization workflows common in medicinal chemistry and materials science.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   38.05
  • LogP   2.4128
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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