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CS-W001157 4
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Ethyl 2-(benzo[d]thiazol-2-yl)acetate

  • CAS No. 29182-42-1

  • Cat. No. CS-W002644
  • Purity≥95%
  • MDL No.MFCD00546397

*For research and further manufacturing use only, not for direct human use.

Ethyl 2-(benzo[d]thiazol-2-yl)acetate|CS-W002644

Structure of 29182-42-1

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General Information

  • CAS No. 29182-42-1
  • Cat. No. CS-W002644
  • Purity ≥95%
  • MDL No. MFCD00546397
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₁NO₂S
  • Molecular Weight 221.28
  • Synonym(s) ETHYL BENZOTHIAZOLYLACETATE
  • SMILES CCOC(CC1=NC2=CC=CC=C2S1)=O

Description

Ethyl 2-(benzo[d]thiazol-2-yl)acetate features a benzothiazole core linked to an ethyl acrylate-like moiety, enabling direct incorporation into heterocyclic frameworks. The electron-deficient thiazole ring enhances reactivity in palladium-catalyzed cross-coupling reactions, while the ester group provides a handle for further derivatization under standard conditions. This compound serves as a robust scaffold for medicinal chemistry and materials synthesis.

Synthesis

  • Route1
    • null|null
      105-56-6
    • null|null
      137-07-5
    • ~80%
    • In-stock
      Ethyl 2-(benzo[d]thiazol-2-yl)acetate|CS-W002644
      29182-42-1

    References

    • Bhusal, Ram Prasad; Yun Cho, Pyo; Kim, Soon-Ai; Park, Hyun; Kim, Hak Sung Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 5 p. 1461 - 1462
  • Route2
    • In-stock
      Ethyl 3-ethoxy-3-iminopropanoate hydrochloride|CS-W019993
      2318-25-4
    • null|null
      137-07-5
    • ~58%
    • In-stock
      Ethyl 2-(benzo[d]thiazol-2-yl)acetate|CS-W002644
      29182-42-1

    References

    • Zakhs; Ponyaev; Subbotina; El'tsov Russian Journal of General Chemistry, 2001 , vol. 71, # 7 p. 1076 - 1087
  • Route3
    • null|null
      880883-60-3
    • ~%
    • In-stock
      Ethyl 2-(benzo[d]thiazol-2-yl)acetate|CS-W002644
      29182-42-1

    References

    • Itoh, Takahiro; Mase, Toshiaki Organic Letters, 2007 , vol. 9, # 18 p. 3687 - 3689

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   39.19
  • LogP   2.4019
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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