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CS-W001157 4
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Ethyl 3-ethoxy-3-iminopropanoate hydrochloride

  • CAS No. 2318-25-4

  • Cat. No. CS-W019993
  • Molecule weight195.64
  • Purity≥95%
  • MDL No.MFCD00051405

*For research and further manufacturing use only, not for direct human use.

Ethyl 3-ethoxy-3-iminopropanoate hydrochloride|CS-W019993

Structure of 2318-25-4

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General Information

  • CAS No. 2318-25-4
  • Cat. No. CS-W019993
  • Purity ≥95%
  • MDL No. MFCD00051405
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClNO₃
  • Molecular Weight 195.64
  • Synonym(s) Propanoic acid, 3-ethoxy-3-imino-, ethyl ester, hydrochloride
  • SMILES CCOC(CC(OCC)=N)=O.Cl

Description

Ethyl 3-ethoxy-3-iminopropanoate hydrochloride features a stabilized iminium ion that enhances reactivity in polar aprotic solvents. This bench-stable derivative integrates readily into Mannich-type reactions and other C–C bond-forming processes, offering improved handling over free base analogs.

Application

Ethyl 3-ethoxy-3-iminopropanoate hydrochloride serves as a versatile synthon in heterocyclic synthesis, enabling efficient access to pyrrolidine and piperidine scaffolds via reductive amination or cyclization protocols. Its iminium functionality exhibits high reactivity toward nucleophiles under mild conditions, while the ethoxy group provides stability and facilitates purification. The hydrochloride salt enhances solubility and handling, making it well-suited for bench-scale applications in medicinal chemistry and process development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   59.38
  • LogP   1.37517
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   4

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