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Structure of 287952-67-4
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4-(4-(Trifluoromethoxy)phenoxy)piperidine features a trifluoromethoxy-substituted aromatic ring linked via an ether bond to a piperidine heterocycle. This combination imparts enhanced lipophilicity and metabolic stability, making the compound valuable for medicinal chemistry applications involving CNS-targeted small molecules.
4-(4-(Trifluoromethoxy)phenoxy)piperidine serves as a versatile building block in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and functionalization protocols. Its trifluoromethoxy-substituted aryl ether moiety confers enhanced metabolic stability and lipophilicity, while the piperidine nitrogen facilitates salt formation and hydrogen bonding. The compound exhibits good bench stability and is compatible with common reaction conditions, simplifying purification and integration into lead optimization campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: