5-Bromo-4-hydroxythiophene-2-carboxylic acid

Name: 5-Bromo-4-hydroxythiophene-2-carboxylic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 2868274-25-1
Cat. No. CS-0637251
Molecule weight223.04
Purity≥98%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-4-hydroxythiophene-2-carboxylic acid|CS-0637251

Structure of 2868274-25-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 2868274-25-1
Cat. No. CS-0637251
Purity ≥98%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₅H₃BrO₃S
Molecular Weight 223.04
Synonym(s) None
SMILES O=C(C1=CC(O)=C(Br)S1)O

Description

5-Bromo-4-hydroxythiophene-2-carboxylic acid features a thiophene core functionalized with bromine, hydroxyl, and carboxylic acid groups at strategic positions. This combination enables direct incorporation into cross-coupling reactions and facilitates conjugation via ester or amide linkages. The hydroxyl group enhances solubility and provides a handle for derivatization, while the electron-withdrawing bromine supports palladium-catalyzed transformations. This molecule serves as a key building block in synthetic routes to bioactive heterocycles and functional materials.

Application

5-Bromo-4-hydroxythiophene-2-carboxylic acid serves as a versatile building block for heterocyclic synthesis, enabling direct functionalization at the 4-position via cross-coupling or derivatization. The carboxylic acid group facilitates amide formation and esterification, while the bromo substituent supports palladium-catalyzed coupling reactions. Its bench-stable nature and compatibility with standard purification methods make it suitable for iterative synthetic sequences in medicinal chemistry and materials science applications.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 57.53
LogP 1.9144
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Carboxylic Acid

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Thiophene compounds

Key Words

2868274-25-1 sigma2868274-25-1 manufacturer2868274-25-1 price2868274-25-1 structure2868274-25-1 SDSbuy 2868274-25-12868274-25-1 supplier2868274-25-1 uses2868274-25-1 molecular weightprice of 2868274-25-12868274-25-1 chemical name formula of 2868274-25-1

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Bromo-4-hydroxythiophene-2-carboxylic acid

CAS No. 2868274-25-1

Recommended Products