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CS-W001157 4
Total: USD 88.00

2-(2-Phenylthiazol-4-yl)acetic acid

  • CAS No. 16441-28-4

  • Cat. No. CS-0186393
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-(2-Phenylthiazol-4-yl)acetic acid|CS-0186393

Structure of 16441-28-4

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General Information

  • CAS No. 16441-28-4
  • Cat. No. CS-0186393
  • Purity ≥96%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₉NO₂S
  • Molecular Weight 219.26
  • Synonym(s) 2-(2-Phenyl-1,3-thiazol-4-yl)acetic acid
  • SMILES C1=CC=C(C=C1)C2=NC(=CS2)CC(=O)O

Description

This acetic acid derivative features a phenylthiazole scaffold that enhances electronic delocalization and steric profile. The carboxylic acid group enables direct coupling in peptide synthesis or metal coordination, while the thiazole ring imparts stability under standard reaction conditions.

Application

2-(2-Phenylthiazol-4-yl)acetic acid serves as a versatile building block for thiazole-based heterocycles, enabling efficient access to bioactive scaffolds through standard coupling and functionalization reactions. Its bench-stable nature and compatibility with diverse reaction conditions facilitate straightforward incorporation into medicinal chemistry programs.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   50.19
  • LogP   2.4372
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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