Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

8-Bromo-1,6-naphthyridine-2-carboxylic acid

  • CAS No. 197507-55-4

  • Cat. No. CS-0200068
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

8-Bromo-1,6-naphthyridine-2-carboxylic acid|CS-0200068

Structure of 197507-55-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 197507-55-4
  • Cat. No. CS-0200068
  • Purity ≥96%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₅BrN₂O₂
  • Molecular Weight 253.05
  • Synonym(s) 8-BROMO-2-CARBOXY[1,6]NAPHTHYRIDINE
  • SMILES C1=CC(=NC2=C1C=NC=C2Br)C(=O)O

Description

8-Bromo-1,6-naphthyridine-2-carboxylic acid features a fused bicyclic core with complementary electron-deficient character and a bromo substituent at the 8-position. This configuration enables direct functionalization via cross-coupling reactions, while the carboxylic acid group facilitates conjugation or salt formation. The compound exhibits bench-stable handling properties and is well-suited for medicinal chemistry applications requiring rigid, polar heterocyclic scaffolds.

Application

8-Bromo-1,6-naphthyridine-2-carboxylic acid serves as a versatile building block for the synthesis of bioactive heterocycles, particularly in medicinal chemistry and agrochemical development. The bromo group enables palladium-catalyzed cross-coupling reactions, while the carboxylic acid facilitates amide bond formation and derivatization. Its stability under standard reaction conditions and compatibility with diverse functional groups make it well-suited for iterative synthetic strategies and scaffold diversification.

Synthesis

  • Route1

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 6 p. 1693 - 1695
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 42, # 16 p. 3023 - 3025
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 42, # 16 p. 3023 - 3025

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   63.08
  • LogP   2.0905
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 197507-55-4 sigma197507-55-4 manufacturer197507-55-4 price197507-55-4 structure197507-55-4 SDSbuy 197507-55-4197507-55-4 supplier197507-55-4 uses197507-55-4 molecular weightprice of 197507-55-4197507-55-4 chemical name formula of 197507-55-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label