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CS-W001157 4
Total: USD 88.00

4-Amino-2-methylphenol

  • CAS No. 2835-96-3

  • Cat. No. CS-W011187
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Amino-2-methylphenol|CS-W011187

Structure of 2835-96-3

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General Information

  • CAS No. 2835-96-3
  • Cat. No. CS-W011187
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₉NO
  • Molecular Weight 123.16
  • Synonym(s) p-Amino-o-cresol
  • SMILES OC1=CC=C(N)C=C1C

Description

4-Amino-2-methylphenol serves as a key intermediate in pharmaceutical synthesis, featuring a nucleophilic amino group flanked by a methyl substituent that enhances reactivity. This ortho-substituted phenol integrates readily into complex heterocycles under standard conditions.

Synthesis

  • Route1

    References

    • Menard, Delphine; Niculescu-Duvaz, Ion; Dijkstra, Harmen P.; Niculescu-Duvaz, Dan; Suijkerbuijk, Bart M. J. M.; Zambon, Alfonso; Nourry, Arnaud; Roman, Esteban; Davies, Lawrence; Manne, Helen A.; Friedlos, Frank; Kirk, Ruth; Whittaker, Steven; Gill, Adrian; Taylor, Richard D.; Marais, Richard; Springer, Caroline J. Journal of Medicinal Chemistry, 2009 , vol. 52, # 13 p. 3881 - 3891
  • Route2
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    • ~%
    • In-stock
      4-Amino-2-methylphenol|CS-W011187
      2835-96-3

    References

    • Chakraborty, Suchandra; Chattopadhyay, Gautam; Saha, Chandan Journal of Heterocyclic Chemistry, 2011 , vol. 48, # 2 p. 331 - 338
  • Route3
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      13362-33-9
    • ~%
    • In-stock
      4-Amino-2-methylphenol|CS-W011187
      2835-96-3

    References

    • Kesten; Johnson; Werbel Journal of Medicinal Chemistry, 1987 , vol. 30, # 5 p. 906 - 911

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   46.25
  • LogP   1.28282
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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