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Structure of 1535-67-7
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Difluoromethylsulfanylbenzene features a uniquely electron-deficient sulfanyl group appended to an aromatic ring, enabling selective functionalization in cross-coupling reactions. This bench-stable arylthiol derivative facilitates the incorporation of fluorinated sulfur motifs into complex molecular architectures under mild conditions.
Difluoromethylsulfanylbenzene serves as a versatile building block for fluorinated aromatic systems, enabling direct introduction of the difluoromethylthio (CF₂H-S) group—known for enhanced metabolic stability and lipophilicity in medicinal chemistry. The sulfanyl functionality facilitates transition metal-catalyzed cross-coupling reactions and acts as a latent electrophile in nucleophilic substitution processes. Its bench-stable nature and compatibility with common functional groups make it ideal for modular synthesis of complex fluorinated scaffolds.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1993
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H225-H315-H319
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P264-P280-P302+P352-P362+P364-P370+P378-P501
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Lot numbers can be found on the outside label of a product: