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(4R,4'R)-2,2'-(Cyclobutane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole)

  • CAS No. 2828431-97-4

  • Cat. No. CS-0179442
  • Purity≥95%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(4R,4'R)-2,2'-(Cyclobutane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole)|CS-0179442

Structure of 2828431-97-4

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General Information

  • CAS No. 2828431-97-4
  • Cat. No. CS-0179442
  • Purity ≥95%
  • MDL No. None
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₈H₃₀N₂O₂
  • Molecular Weight 306.44
  • Synonym(s) None
  • SMILES CC(C)(C)[C@H]1N=C(C2(CCC2)C3=N[C@H](C(C)(C)C)CO3)OC1

Description

This cyclobutane-linked bisoxazole features two sterically shielded dihydrooxazole rings, offering enhanced stability and solubility in organic media. The (4R,4'R) stereochemistry ensures predictable conformational behavior, enabling reliable use in asymmetric synthesis and chiral ligand design.

Application

(4R,4'R)-2,2'-(Cyclobutane-1,1-diyl)bis(4-(tert-butyl)-4,5-dihydrooxazole) serves as a stereochemically defined chiral scaffold for asymmetric synthesis, enabling controlled construction of complex heterocyclic architectures. Its robust cyclobutane core and stable dihydrooxazole rings offer excellent bench stability, tolerance to diverse reaction conditions, and ease of purification—ideal for iterative functionalization in medicinal chemistry and catalyst design workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   43.18
  • LogP   3.8435
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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