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Structure of 28177-52-8
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2-Chloro-6-iodophenol features a phenolic hydroxyl group flanked by chlorine and iodine substituents at the 2- and 6-positions, respectively. This electron-deficient aromatic framework enables selective coupling reactions in synthetic organic chemistry. The molecule exhibits bench-stable handling characteristics and serves as a valuable intermediate in the construction of complex heterocycles and functionalized aryl derivatives.
2-Chloro-6-iodophenol serves as a valuable building block for the synthesis of functionalized aromatic scaffolds, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The chloro group provides stability and selective transformation potential, while the iodo substituent facilitates efficient coupling under mild conditions. Its bench-stable nature and compatibility with diverse reaction conditions make it well-suited for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: