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Structure of 71643-66-8
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4-Chloro-2-iodophenol features a phenolic hydroxyl group flanked by chlorine and iodine substituents, enabling selective coupling reactions in medicinal chemistry. The electron-withdrawing halogens enhance reactivity in palladium-catalyzed cross-couplings, while the ortho-iodo moiety offers a strategic handle for further functionalization. This bench-stable compound serves as a key building block for bioactive molecule synthesis.
4-Chloro-2-iodophenol serves as a versatile building block in the synthesis of pharmaceutical intermediates and functionalized heterocycles. Its ortho-iodo group enables palladium-catalyzed cross-coupling reactions, while the phenolic hydroxyl and chloro substituents offer complementary sites for further derivatization. The compound exhibits good bench stability and facilitates efficient purification, making it well-suited for scalable synthetic workflows in medicinal chemistry and process development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: