Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Spiro[3.3]heptane-2-carboxylic acid

  • CAS No. 28114-87-6

  • Cat. No. CS-0048687
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Spiro[3.3]heptane-2-carboxylic acid|CS-0048687

Structure of 28114-87-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 28114-87-6
  • Cat. No. CS-0048687
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂O₂
  • Molecular Weight 140.18
  • Synonym(s) heptane-3-carboxylic acid">spiroheptane-3-carboxylic acid
  • SMILES OC(=O)C1CC2(CCC2)C1

Description

Spiro[3.3]heptane-2-carboxylic acid features a rigid, three-dimensional spirocyclic core that imparts exceptional stereochemical stability and spatial control. The carboxylic acid group enables direct functionalization or derivatization under standard conditions. This scaffold integrates readily into molecular architectures requiring constrained geometry and enhanced metabolic resilience.

Application

Spiro[3.3]heptane-2-carboxylic acid serves as a rigid, three-dimensional building block for medicinal chemistry and materials science. Its spirocyclic core imparts conformational stability and enhances metabolic resistance, while the carboxylic acid functionality enables direct derivatization via amide, ester, or salt formation. The compound exhibits excellent bench stability and facilitates purification by standard chromatographic methods, making it well-suited for high-throughput synthesis and structure-activity studies.

Synthesis

  • Route1
    • Diethyl spiro[3.3]heptane-2,2-dicarboxylate|CS-1145276
      64775-96-8
    • ~%
    • In-stock
      Spiro[3.3]heptane-2-carboxylic acid|CS-0048687
      28114-87-6

    References

    • Buchta,E.; Geibel,K. Justus Liebigs Annalen der Chemie, 1961 , vol. 648, p. 36 - 50
  • Route2
    • Cyclobutane-1,1-diylbis(methylene) bis(4-methylbenzenesulfonate)|CS-0505881
      22308-09-4
    • ~%
    • In-stock
      Spiro[3.3]heptane-2-carboxylic acid|CS-0048687
      28114-87-6

    References

    • Buchta,E.; Geibel,K. Justus Liebigs Annalen der Chemie, 1961 , vol. 648, p. 36 - 50
  • Route3
    • Spiro[3.3]heptane-2,2-dicarboxylic acid|CS-0726257
      64775-97-9
    • ~%
    • In-stock
      Spiro[3.3]heptane-2-carboxylic acid|CS-0048687
      28114-87-6

    References

    • Buchta,E.; Geibel,K. Justus Liebigs Annalen der Chemie, 1961 , vol. 648, p. 36 - 50

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.6513
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Spiro[3.3]heptane-2-carboxylic acid sigmaSpiro[3.3]heptane-2-carboxylic acid manufacturerSpiro[3.3]heptane-2-carboxylic acid priceSpiro[3.3]heptane-2-carboxylic acid structureSpiro[3.3]heptane-2-carboxylic acid SDSbuy Spiro[3.3]heptane-2-carboxylic acidSpiro[3.3]heptane-2-carboxylic acid supplierSpiro[3.3]heptane-2-carboxylic acid usesSpiro[3.3]heptane-2-carboxylic acid molecular weightprice of Spiro[3.3]heptane-2-carboxylic acidSpiro[3.3]heptane-2-carboxylic acid chemical name formula of Spiro[3.3]heptane-2-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label