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CS-W001157 4
Total: USD 88.00

Spiro[2.3]hexane-1-carboxylic acid

  • CAS No. 17202-56-1

  • Cat. No. CS-0048697
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Spiro[2.3]hexane-1-carboxylic acid|CS-0048697

Structure of 17202-56-1

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General Information

  • CAS No. 17202-56-1
  • Cat. No. CS-0048697
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₀O₂
  • Molecular Weight 126.15
  • Synonym(s) rac-(R)-spiro[2.3]hexane-1-carboxylic acid
  • SMILES OC(=O)C1CC11CCC1

Description

Spiro[2.3]hexane-1-carboxylic acid features a rigid spirocyclic core that imparts exceptional conformational stability, enabling precise spatial control in molecular design. The carboxylic acid group provides a versatile handle for derivatization, facilitating integration into diverse synthetic scaffolds. This compound serves as a valuable building block in the development of bioactive molecules and functional materials.

Application

Spiro[2.3]hexane-1-carboxylic acid serves as a rigid, three-dimensional building block for medicinal chemistry and asymmetric synthesis. Its spirocyclic core imparts conformational constraint, enhancing target selectivity in bioactive molecule design. The carboxylic acid group enables straightforward derivatization via esterification, amide coupling, or decarboxylation protocols. Bench-stable and compatible with standard reaction conditions, it facilitates the construction of complex heterocycles and natural product analogs.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.2612
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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