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CS-W001157 4
Total: USD 88.00

4-(Morpholinylmethyl)phenylboronic acid

  • CAS No. 279262-23-6

  • Cat. No. CS-W000908
  • Purity≥97%
  • MDL No.MFCD06801707
  • HazMat Fee +

    HazMat Fee

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

    The shipment is processed through FedEx Ground under the Limited Quantity option.

    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

4-(Morpholinylmethyl)phenylboronic acid|CS-W000908

Structure of 279262-23-6

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Description

4-(Morpholinylmethyl)phenylboronic acid features a boronic acid group appended to a phenyl ring bearing a morpholinylmethyl substituent. This configuration enables efficient Suzuki-Miyaura coupling under mild conditions, with the morpholinyl moiety enhancing solubility and stability in aqueous-organic media. The compound serves as a key building block for biologically active arylated scaffolds in medicinal chemistry and materials synthesis.

Application

4-(Morpholinylmethyl)phenylboronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds. The morpholinylmethyl group imparts enhanced solubility and metabolic stability, while the boronic acid functionality ensures reliable coupling under mild conditions. Its bench-stable solid form and tolerance to common functional groups facilitate straightforward handling and purification in medicinal chemistry and process synthesis workflows.

General Information

  • CAS No. 279262-23-6
  • Cat. No. CS-W000908
  • Purity ≥97%
  • MDL No. MFCD06801707
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆BNO₃
  • Molecular Weight 221.06
  • Synonym(s) Boronicacid, [4-(4-morpholinylmethyl)phenyl]-
  • SMILES OB(O)C1=CC=C(CN2CCOCC2)C=C1

Computational Chemistry Data

  • TPSA   52.93
  • LogP   -0.8014
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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