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CS-W001157 4
Total: USD 88.00

(2-(Morpholinomethyl)phenyl)boronic acid

  • CAS No. 223433-45-2

  • Cat. No. CS-0156644
  • Molecule weight221.06
  • Purity≥97%
  • MDL No.MFCD01319041

*For research and further manufacturing use only, not for direct human use.

(2-(Morpholinomethyl)phenyl)boronic acid|CS-0156644

Structure of 223433-45-2

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General Information

  • CAS No. 223433-45-2
  • Cat. No. CS-0156644
  • Purity ≥97%
  • MDL No. MFCD01319041
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₆BNO₃
  • Molecular Weight 221.06
  • Synonym(s) 2-(Morpholinomethyl)phenylboronic acid
  • SMILES C1=CC=C(C(=C1)CN2CCOCC2)B(O)O

Description

This boronate moiety integrates a morpholinomethyl group at the ortho position of a phenyl ring, delivering enhanced solubility and stability under standard conditions. The electron-rich morpholine unit improves reactivity in Suzuki-Miyaura couplings while maintaining bench-stable handling characteristics.

Application

(2-(Morpholinomethyl)phenyl)boronic acid serves as a versatile building block in Suzuki-Miyaura coupling reactions, enabling efficient C–C bond formation under mild conditions. Its morpholinomethyl group enhances solubility and functional group tolerance, while the boronic acid moiety offers stability and ease of purification. This reagent facilitates the synthesis of biaryl scaffolds common in pharmaceutical development and materials science.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   52.93
  • LogP   -0.8014
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   3

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