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Structure of 278788-60-6
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(R)-1-Boc-piperazine-2-carboxylic acid features a chiral piperazine core with a Boc-protected carboxylic acid, enabling selective incorporation into peptide and small-molecule scaffolds. The stereochemistry at the 2-position ensures precise spatial orientation in bioactive compounds. This bench-stable derivative facilitates efficient synthesis of nitrogen-rich heterocycles and serves as a key intermediate in medicinal chemistry campaigns requiring controlled functionalization.
(R)-1-Boc-piperazine-2-carboxylic acid serves as a versatile chiral building block for the synthesis of piperazinone-containing scaffolds in medicinal chemistry. The Boc group provides stability and facilitates straightforward deprotection under mild acidic conditions. Its carboxylic acid functionality enables direct coupling with amines or activation for amide formation, while the piperazine core offers favorable solubility and hydrogen-bonding capacity. This compound functions reliably in multi-step syntheses requiring stereocontrolled access to functionalized heterocycles.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: