Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

1-Boc-piperazine-3-carboxylic acid

  • CAS No. 128019-59-0

  • Cat. No. CS-D0652
  • Purity≥97%
  • MDL No.MFCD01076218

*For research and further manufacturing use only, not for direct human use.

1-Boc-piperazine-3-carboxylic acid|CS-D0652

Structure of 128019-59-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 128019-59-0
  • Cat. No. CS-D0652
  • Purity ≥97%
  • MDL No. MFCD01076218
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₈N₂O₄
  • Molecular Weight 230.26
  • Synonym(s) N-4-Boc-2-piperazinecarboxylic acid
  • SMILES O=C(OC(C)(C)C)N1CC(NCC1)C(O)=O

Description

1-Boc-piperazine-3-carboxylic acid features a protected piperazine core with a carboxylic acid functionality, enabling direct incorporation into peptide and small-molecule scaffolds. The Boc group ensures stability during synthesis and facilitates selective deprotection under mild acidic conditions. This derivative serves as a key building block in medicinal chemistry for constructing bioactive heterocycles.

Application

1-Boc-piperazine-3-carboxylic acid serves as a versatile building block for medicinal chemistry and peptide synthesis, enabling efficient access to piperazine-containing scaffolds. The Boc group provides excellent stability and orthogonal protection, facilitating straightforward deprotection under mild acidic conditions. It functions as a key intermediate in the construction of heterocyclic APIs and bioactive molecules, demonstrating broad compatibility with standard coupling and functionalization protocols.

Synthesis

  • Route1

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 13, # 23 p. 4241 - 4244
  • Route2

    References

    • WO2005/44797 A1, ; Page/Page column 92 ; WO 2005/044797 A1
  • Route3

    References

    • Journal of Medicinal Chemistry, , vol. 43, # 3 p. 369 - 380

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H319
Precautionary Statements : P261-P264-P272-P280-P302+P352-P362+P364-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   78.87
  • LogP   0.2799
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1-Boc-piperazine-3-carboxylic acid sigma1-Boc-piperazine-3-carboxylic acid manufacturer1-Boc-piperazine-3-carboxylic acid price1-Boc-piperazine-3-carboxylic acid structure1-Boc-piperazine-3-carboxylic acid SDSbuy 1-Boc-piperazine-3-carboxylic acid1-Boc-piperazine-3-carboxylic acid supplier1-Boc-piperazine-3-carboxylic acid uses1-Boc-piperazine-3-carboxylic acid molecular weightprice of 1-Boc-piperazine-3-carboxylic acid1-Boc-piperazine-3-carboxylic acid chemical name formula of 1-Boc-piperazine-3-carboxylic acid
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label