(-)-(S)-1-(2-Pyridyl)ethanamine

Name: (-)-(S)-1-(2-Pyridyl)ethanamine
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CAS No. 27854-90-6
Cat. No. CS-M3539
Purity≥97%
MDL No.MFCD08752493

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Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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(-)-(S)-1-(2-Pyridyl)ethanamine|CS-M3539

Structure of 27854-90-6

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General Information

CAS No. 27854-90-6
Cat. No. CS-M3539
Purity ≥97%
MDL No. MFCD08752493
Storage -20°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₁₀N₂
Molecular Weight 122.17
Synonym(s) 2-PyridineMethanaMine, a-Methyl-, (S)-
SMILES N[C@H](C1=NC=CC=C1)C

Description

This chiral amine features a pyridyl ring directly attached to a stereogenic carbon, enabling selective coordination in asymmetric synthesis. The (S)-configuration imparts defined stereochemical control, while the basic nitrogen and aromatic system facilitate metal complexation and hydrogen bonding. This structure supports efficient ligand design for catalytic transformations requiring precise spatial orientation.

Application

(-)-(S)-1-(2-Pyridyl)ethanamine serves as a chiral auxiliary and ligand in asymmetric synthesis, enabling stereoselective transformations through well-documented coordination with transition metals. Its pyridyl moiety provides strong binding affinity for catalytic centers, while the chiral α-amino group facilitates enantiocontrol in C–C and C–heteroatom bond formations. The compound exhibits excellent bench stability, ease of handling, and compatibility with common reaction conditions, making it a reliable building block for pharmaceutical intermediates and catalyst development.

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 38.91
LogP 1.1013
H_Acceptors 2
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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(-)-(S)-1-(2-Pyridyl)ethanamine

CAS No. 27854-90-6

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