Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Methyl 2-benzoxazolecarboxylate

  • CAS No. 27383-86-4

  • Cat. No. CS-0061868
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Methyl 2-benzoxazolecarboxylate|CS-0061868

Structure of 27383-86-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 27383-86-4
  • Cat. No. CS-0061868
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇NO₃
  • Molecular Weight 177.16
  • Synonym(s) Methyl benzo[d]oxazole-2-carboxylate
  • SMILES COC(=O)C1=NC2=CC=CC=C2O1

Description

Methyl 2-benzoxazolecarboxylate features a benzoxazole scaffold with a methyl ester at the 2-position, offering enhanced solubility and stability under standard conditions. This derivative serves as a key intermediate in the synthesis of bioactive heterocycles, particularly in pharmaceutical research targeting kinase inhibitors and antitumor agents.

Application

Methyl 2-benzoxazolecarboxylate serves as a versatile building block in heterocyclic synthesis, enabling efficient access to benzoxazole-based scaffolds prevalent in pharmaceuticals and agrochemicals. Its carboxylate functionality facilitates nucleophilic substitution, palladium-catalyzed coupling reactions, and derivatization under mild conditions. The molecule exhibits good bench stability, ease of purification, and compatibility with diverse functional groups, making it well-suited for iterative synthetic strategies in medicinal chemistry and process development.

Synthesis

  • Route1
    • In-stock
      Benzoxazole|CS-W004722
      273-53-0
    • null|null
      124-38-9
    • null|null
      74-88-4
    • ~90%
    • In-stock
      Methyl 2-benzoxazolecarboxylate|CS-0061868
      27383-86-4

    References

    • Boogaerts, Ine I. F.; Nolan, Steven P. Journal of the American Chemical Society, 2010 , vol. 132, # 26 p. 8858 - 8859
  • Route2
    • null|null
      67-56-1
    • null|null
      408538-63-6
    • ~73%
    • In-stock
      Methyl 2-benzoxazolecarboxylate|CS-0061868
      27383-86-4

    References

    • Vodela, Sunil; Mekala, Raghu Vardhan Reddy; Danda, Ravinder Reddy; Kodhati, Venkateshwarlu Chinese Chemical Letters, 2013 , vol. 24, # 7 p. 625 - 628
  • Route3
    • In-stock
      Methyl 2,2,2-trimethoxyacetate|CS-W005715
      18370-95-1
    • null|null
      95-55-6
    • ~61%
    • In-stock
      Methyl 2-benzoxazolecarboxylate|CS-0061868
      27383-86-4

    References

    • Musser, J. H.; Hudec, T. T.; Bailey, K. Synthetic Communications, 1984 , vol. 14, # 10 p. 947 - 954

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   52.33
  • LogP   1.6144
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • Methyl 2-benzoxazolecarboxylate sigmaMethyl 2-benzoxazolecarboxylate manufacturerMethyl 2-benzoxazolecarboxylate priceMethyl 2-benzoxazolecarboxylate structureMethyl 2-benzoxazolecarboxylate SDSbuy Methyl 2-benzoxazolecarboxylateMethyl 2-benzoxazolecarboxylate supplierMethyl 2-benzoxazolecarboxylate usesMethyl 2-benzoxazolecarboxylate molecular weightprice of Methyl 2-benzoxazolecarboxylateMethyl 2-benzoxazolecarboxylate chemical name formula of Methyl 2-benzoxazolecarboxylate
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label