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CS-W001157 4
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Fmoc-(S)-3-amino-4-(3-fluorophenyl)-butyric acid

  • CAS No. 270596-52-6

  • Cat. No. CS-0062058
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Fmoc-(S)-3-amino-4-(3-fluorophenyl)-butyric acid|CS-0062058

Structure of 270596-52-6

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General Information

  • CAS No. 270596-52-6
  • Cat. No. CS-0062058
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₂₂FNO₄
  • Molecular Weight 419.44
  • Synonym(s) Fmoc-(S)-3-Amino-4-(3-fluoro-phenyl)-butyric acid
  • SMILES FC1=CC=CC(C[C@@H](CC(O)=O)NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)=C1

Description

Fmoc-(S)-3-Amino-4-(3-fluorophenyl)-butyric acid is a fluorinated amino acid derivative featuring a benzyl side chain with a para-fluorophenyl substituent. This sterically defined, bench-stable building block integrates seamlessly into peptide synthesis, delivering enhanced solubility and structural diversity for bioactive peptide design.

Application

Fmoc-(S)-3-Amino-4-(3-fluorophenyl)-butyric acid serves as a versatile building block for the synthesis of peptide-based pharmaceuticals and bioactive molecules. The Fmoc group enables efficient solid-phase peptide synthesis, while the 3-fluorophenyl moiety imparts metabolic stability and modulates electronic properties. Its amino and carboxylic acid functionalities support standard coupling reactions, offering excellent bench stability and compatibility with orthogonal protection strategies.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   4.7502
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   7

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