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CS-W001157 4
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(R)-1-(tert-Butoxycarbonyl)-3,3-dimethyl-1,3-azasilolidine-5-carboxylic acid

  • CAS No. 268224-29-9

  • Cat. No. CS-W004250
  • Purity≥95%
  • MDL No.MFCD19689677

*For research and further manufacturing use only, not for direct human use.

(R)-1-(tert-Butoxycarbonyl)-3,3-dimethyl-1,3-azasilolidine-5-carboxylic acid|CS-W004250

Structure of 268224-29-9

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General Information

  • CAS No. 268224-29-9
  • Cat. No. CS-W004250
  • Purity ≥95%
  • MDL No. MFCD19689677
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₂₁NO₄Si
  • Molecular Weight 259.37
  • Synonym(s) (5R)-3,3-Dimethyl-1-aza-3-silacyclopentane-1,5-dicarboxylic acid 1-tert-butyl ester
  • SMILES O=C(N1C[Si](C)(C)C[C@H]1C(O)=O)OC(C)(C)C

Synthesis

  • Route1
    • 1-(Tert-butyl) 5-methyl (R)-3,3-dimethyl-1,3-azasilolidine-1,5-dicarboxylate|CS-1075664
      268224-27-7
    • ~10%
    • In-stock
      (R)-1-(tert-Butoxycarbonyl)-3,3-dimethyl-1,3-azasilolidine-5-carboxylic acid|CS-W004250
      268224-29-9

    References

    • BRISTOL-MYERS SQUIBB COMPANY; KIM, Kyoung S. Patent: WO2014/11712 A1, 2014 ; Location in patent: Paragraph 00133; 00137 ;
  • Route2
    • null|null
      1334313-74-4
    • ~%
    • In-stock
      (R)-1-(tert-Butoxycarbonyl)-3,3-dimethyl-1,3-azasilolidine-5-carboxylic acid|CS-W004250
      268224-29-9

    References

    • McKinnell, Robert Murray; Long, Daniel D. Patent: US2013/287731 A1, 2013 ; Location in patent: Paragraph 0269 ;
  • Route3
    • null|null
      268224-19-7
    • ~%
    • In-stock
      (R)-1-(tert-Butoxycarbonyl)-3,3-dimethyl-1,3-azasilolidine-5-carboxylic acid|CS-W004250
      268224-29-9

    References

    • Vivet, Bertrand; Cavelier, Florine; Martinez, Jean European Journal of Organic Chemistry, 2000 , # 5 p. 807 - 811

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   1.9379
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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