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CS-W001157 4
Total: USD 88.00

7-Aminocephalosporanic acid

  • CAS No. 957-68-6

  • Cat. No. CS-4823
  • Purity≥98%
  • MDL No.MFCD00005177

*For research and further manufacturing use only, not for direct human use.

7-Aminocephalosporanic acid|CS-4823

Structure of 957-68-6

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General Information

  • CAS No. 957-68-6
  • Cat. No. CS-4823
  • Purity ≥98%
  • MDL No. MFCD00005177
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₂N₂O₅S
  • Molecular Weight 272.28
  • Synonym(s) 7-ACA
  • SMILES O=C(C(N12)=C(COC(C)=O)CS[C@]2([H])[C@H](N)C1=O)O

Description

Chemical structure: -lactam7-Aminocephalosporanic acid (7-ACA) can be used as a starting material to synthesize: Cefotaxime by acylation reaction with S-benzothiazol-2-yl(2-amino-4-thiazolyl)(methoxyimino)thioacetate (MAEM) in the presence of triethylamine.Cefpodoxime proxetil, a third-generation antibiotic via cefotaxime intermediate.Sodium 3-substituted cephalosporanate sulfone derivatives as potential inhibitors of -lactamase.

Synthesis

  • Route1

    References

    • Advanced Synthesis and Catalysis, , vol. 347, # 14 p. 1804 - 1810
  • Route2

    References

    • Fernandez-Lafuente, Roberto; Guisan, Jose M.; Pregnolato, Massimo; Terreni, Marco Tetrahedron Letters, 1997 , vol. 38, # 26 p. 4693 - 4696
  • Route3
    • null|null
      27920-90-7
    • ~%
    • In-stock
      Glutaric acid|CS-W009536
      110-94-1
    • In-stock
      7-Aminocephalosporanic acid|CS-4823
      957-68-6

    References

    • Advanced Synthesis and Catalysis, , vol. 347, # 14 p. 1804 - 1810

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H334
Precautionary Statements : P261-P272-P280-P285-P302+P352-P363-P501

Quality Control

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Computational Chemistry Data

  • TPSA   109.93
  • LogP   -0.8694
  • H_Acceptors   6
  • H_Donors   2
  • Rotatable_Bonds   3

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