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CS-W001157 4
Total: USD 88.00

4-Bromo-3-(hydroxymethyl)benzaldehyde

  • CAS No. 254744-15-5

  • Cat. No. CS-0157115
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromo-3-(hydroxymethyl)benzaldehyde|CS-0157115

Structure of 254744-15-5

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General Information

  • CAS No. 254744-15-5
  • Cat. No. CS-0157115
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇BrO₂
  • Molecular Weight 215.04
  • Synonym(s) None
  • SMILES C1=CC(=C(C=C1C=O)CO)Br

Description

4-Bromo-3-(hydroxymethyl)benzaldehyde features a bromine substituent at the para position relative to the aldehyde, enhancing electrophilic reactivity. The adjacent hydroxymethyl group provides a handle for derivatization, while the aldehyde moiety enables direct incorporation into coupling reactions. This compound serves as a key intermediate in the synthesis of functionalized aromatic systems and bioactive molecules.

Application

4-Bromo-3-(hydroxymethyl)benzaldehyde serves as a versatile building block in medicinal chemistry and materials synthesis, enabling efficient access to functionalized aromatic scaffolds. The aldehyde group facilitates nucleophilic additions and condensation reactions, while the bromide supports palladium-catalyzed cross-couplings. The hydroxymethyl functionality offers additional handles for derivatization or protection, enhancing synthetic flexibility. Its bench-stable nature and compatibility with common reaction conditions make it a practical choice for multi-step syntheses.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   1.7539
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   2

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