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CS-W001157 4
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4-Bromo-2,6-dichlorobenzaldehyde

  • CAS No. 111829-72-2

  • Cat. No. CS-0067891
  • Purity≥98%
  • MDL No.MFCD11227147

*For research and further manufacturing use only, not for direct human use.

4-Bromo-2,6-dichlorobenzaldehyde|CS-0067891

Structure of 111829-72-2

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General Information

  • CAS No. 111829-72-2
  • Cat. No. CS-0067891
  • Purity ≥98%
  • MDL No. MFCD11227147
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₃BrCl₂O
  • Molecular Weight 253.91
  • Synonym(s) Benzaldehyde, 4-bromo-2,6-dichloro-
  • SMILES O=CC1=C(Cl)C=C(Br)C=C1Cl

Description

4-Bromo-2,6-dichlorobenzaldehyde features a trifunctional aromatic core with bromo and two chloro substituents positioned ortho and para to the aldehyde group. This electron-deficient scaffold enables direct coupling in cross-coupling reactions, offering high functional group tolerance and stability under standard conditions.

Application

4-Bromo-2,6-dichlorobenzaldehyde serves as a versatile building block in medicinal chemistry and materials synthesis, enabling direct functionalization at the aldehyde position. Its electron-deficient aromatic core enhances reactivity in nucleophilic addition and coupling reactions. The ortho-chlorine substituents provide steric control and stability, while the bromine offers a handle for palladium-catalyzed cross-coupling. Bench-stable and readily purified by recrystallization, it functions reliably in multistep syntheses of heterocyclic scaffolds and API intermediates.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   3.5684
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   1

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