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CS-W001157 4
Total: USD 88.00

Azetidine-2-carboxylic acid

  • CAS No. 2517-04-6

  • Cat. No. CS-M0178
  • Purity≥97%
  • MDL No.MFCD00066660

*For research and further manufacturing use only, not for direct human use.

Azetidine-2-carboxylic acid|CS-M0178

Structure of 2517-04-6

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General Information

  • CAS No. 2517-04-6
  • Cat. No. CS-M0178
  • Purity ≥97%
  • MDL No. MFCD00066660
  • Storage 4°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇NO₂
  • Molecular Weight 101.10
  • Synonym(s) None
  • SMILES O=C(O)C1NCC1

Description

Azetidine-2-carboxylic acid serves as a conformationally constrained proline analog, integrating a strained four-membered ring that enforces specific backbone geometries in peptide systems. This structural rigidity enhances secondary structure stability and improves metabolic resistance in bioactive peptides.

Synthesis

  • Route1
    • null|null
      22742-42-3
    • ~%
    • In-stock
      Azetidine-2-carboxylic acid|CS-M0178
      2517-04-6

    References

    • Tetrahedron Asymmetry, , vol. 3, # 7 p. 859 - 862
  • Route2
    • (S)-1-Tosylazetidine-2-carboxylic acid|CS-0162113
      39897-13-7
    • ~%
    • In-stock
      Azetidine-2-carboxylic acid|CS-M0178
      2517-04-6

    References

    • Journal of Medicinal Chemistry, , vol. 39, # 4 p. 817 - 825
  • Route3
    • γ-Aminobutyric acid Vigabatrin  Impurity|CS-0228792
      56-12-2
    • ~%
    • In-stock
      Azetidine-2-carboxylic acid|CS-M0178
      2517-04-6

    References

    • Biochemical Journal, , vol. 64, p. 323,330

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   -0.5671
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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