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CS-W001157 4
Total: USD 88.00

(R)-Azetidine-2-carboxylic acid

  • CAS No. 7729-30-8

  • Cat. No. CS-W018478
  • Purity≥97%
  • MDL No.MFCD00800731

*For research and further manufacturing use only, not for direct human use.

(R)-Azetidine-2-carboxylic acid|CS-W018478

Structure of 7729-30-8

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General Information

  • CAS No. 7729-30-8
  • Cat. No. CS-W018478
  • Purity ≥97%
  • MDL No. MFCD00800731
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₇NO₂
  • Molecular Weight 101.10
  • Synonym(s) None
  • SMILES O=C([C@@H]1NCC1)O

Description

(R)-Azetidine-2-carboxylic acid is a conformationally constrained, stereodefined amino acid analog featuring a strained four-membered ring that imparts rigidity to peptide backbones. This structural motif enhances proteolytic stability and modulates bioavailability in peptidomimetic drug design. The (R)-enantiomer provides precise stereochemical control for applications in medicinal chemistry and catalytic synthesis.

Synthesis

  • Route1
    • null|null
      249734-37-0
    • ~98%
    • In-stock
      (R)-Azetidine-2-carboxylic acid|CS-W018478
      7729-30-8

    References

    • Couty, Francois; Evano, Gwilherm; Vargas-Sanchez, Monica; Bouzas, Gloria Journal of Organic Chemistry, 2005 , vol. 70, # 22 p. 9028 - 9031
  • Route2
    • (R)-1-((Benzyloxy)carbonyl)azetidine-2-carboxylic acid|CS-0270042
      25654-51-7
    • ~%
    • In-stock
      (R)-Azetidine-2-carboxylic acid|CS-W018478
      7729-30-8

    References

    • Journal of Medicinal Chemistry, , vol. 41, # 4 p. 407 - 412
  • Route3

    References

    • Biochemical Journal, , vol. 64, p. 323,330

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   49.33
  • LogP   -0.5671
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   1

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