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CS-W001157 4
Total: USD 88.00

1-Boc-L-azetidine-2-carboxylic acid

  • CAS No. 51077-14-6

  • Cat. No. CS-W007586
  • Purity≥95%
  • MDL No.MFCD01321011

*For research and further manufacturing use only, not for direct human use.

1-Boc-L-azetidine-2-carboxylic acid|CS-W007586

Structure of 51077-14-6

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General Information

  • CAS No. 51077-14-6
  • Cat. No. CS-W007586
  • Purity ≥95%
  • MDL No. MFCD01321011
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₅NO₄
  • Molecular Weight 201.22
  • Synonym(s) None
  • SMILES O=C([C@H]1N(C(OC(C)(C)C)=O)CC1)O

Description

1-Boc-L-azetidine-2-carboxylic acid features a strained four-membered azetidine ring functionalized with a carboxylic acid and a Boc protecting group. This configuration enables direct incorporation into peptide chains or use in synthetic routes requiring stable, electron-rich heterocyclic scaffolds under standard bench conditions.

Application

1-Boc-L-azetidine-2-carboxylic acid serves as a stable, bench-ready building block for the synthesis of bioactive azetidine-containing peptides and heterocyclic scaffolds. Its protected amine and carboxylic acid functionalities enable straightforward coupling reactions and orthogonal deprotection sequences. The Boc group ensures excellent stability during storage and handling, while the strained azetidine ring provides unique conformational constraints valuable in medicinal chemistry. Functions reliably in standard peptide coupling protocols and facilitates access to diverse API-relevant architectures.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   1.0804
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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