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CS-W001157 4
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3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pentanedioic acid

  • CAS No. 247217-28-3

  • Cat. No. CS-0372618
  • Purity≥98%
  • MDL No.MFCD03002700

*For research and further manufacturing use only, not for direct human use.

3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pentanedioic acid|CS-0372618

Structure of 247217-28-3

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General Information

  • CAS No. 247217-28-3
  • Cat. No. CS-0372618
  • Purity ≥98%
  • MDL No. MFCD03002700
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₁₉NO₆
  • Molecular Weight 369.37
  • Synonym(s) Fmoc-beta-homoaspartic acid
  • SMILES O=C(O)CC(NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CC(O)=O

Description

This fluorenylmethoxycarbonyl-protected glutaric acid derivative serves as a robust linker for peptide synthesis and bioconjugation. Featuring a stable C-terminal carboxylate and an orthogonal Fmoc group, it enables efficient chain elongation under mild conditions while resisting premature deprotection.

Application

3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)pentanedioic acid serves as a robust, bench-stable amino acid derivative enabling efficient solid-phase peptide synthesis. The Fmoc group provides orthogonal protection with high deprotection fidelity, while the flanking glutamic acid-like side chain facilitates incorporation into peptide backbones and supports diverse functionalization. Its well-defined reactivity profile ensures reliable coupling and minimal racemization, making it ideal for constructing complex peptide sequences under standard synthetic conditions.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H332
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P501

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Computational Chemistry Data

  • TPSA   112.93
  • LogP   2.8431
  • H_Acceptors   4
  • H_Donors   3
  • Rotatable_Bonds   7

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