Fmoc-S-3-amino-5-hexynic acid

Name: Fmoc-S-3-amino-5-hexynic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1217669-02-7
Cat. No. CS-0182726
Purity≥95%
MDL No.MFCD01861008

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Fmoc-S-3-amino-5-hexynic acid|CS-0182726

Structure of 1217669-02-7

Size

Price

Quantity

* Please select Quantity before adding items.

Description

Fmoc-S-3-amino-5-hexynic acid integrates a terminal alkyne and primary amine for bioorthogonal conjugation. This bifunctional reagent enables site-specific labeling via CuAAC or strain-promoted reactions, combining high reactivity with stability under standard conditions. The Fmoc group facilitates efficient solid-phase synthesis and protection of the amine.

Application

Fmoc-S-3-amino-5-hexynic acid serves as a versatile building block for the synthesis of peptidomimetics and bioconjugates. Its terminal alkyne enables efficient copper-catalyzed azide-alkyne cycloaddition (CuAAC), while the Fmoc-protected amine and carboxylic acid facilitate standard solid-phase peptide synthesis. The molecule exhibits excellent bench stability, ease of purification, and compatibility with diverse functional groups, making it ideal for constructing complex scaffolds in medicinal chemistry and chemical biology workflows.

General Information

CAS No. 1217669-02-7
Cat. No. CS-0182726
Purity ≥95%
MDL No. MFCD01861008
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₁H₁₉NO₄
Molecular Weight 349.38
Synonym(s) FMoc-(S)-3-AMino-5-hexynoic acid
SMILES C#CC[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CC(O)=O

Computational Chemistry Data

TPSA 75.63
LogP 3.3917
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 6

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS06
Signal Word : Danger	UN#: 2811
Class : 6.1	Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Alkyne

Building Blocks Functional Group Carboxylic Acid

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Life Science Click Chemistry Reagents Alkyne

Chemical Biology Pharmaceutical Development and Drug Discovery Research Conjugation Chemistry/Click Chemistry Terminal Alkynes

Chemical Biology Conjugation Chemistry/Click Chemistry Terminal Alkynes

Key Words

Fmoc-S-3-amino-5-hexynic acid sigmaFmoc-S-3-amino-5-hexynic acid manufacturerFmoc-S-3-amino-5-hexynic acid priceFmoc-S-3-amino-5-hexynic acid structureFmoc-S-3-amino-5-hexynic acid SDSbuy Fmoc-S-3-amino-5-hexynic acidFmoc-S-3-amino-5-hexynic acid supplierFmoc-S-3-amino-5-hexynic acid usesFmoc-S-3-amino-5-hexynic acid molecular weightprice of Fmoc-S-3-amino-5-hexynic acidFmoc-S-3-amino-5-hexynic acid chemical name formula of Fmoc-S-3-amino-5-hexynic acid

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Fmoc-S-3-amino-5-hexynic acid

CAS No. 1217669-02-7

Recommended Products