Lot numbers can be found on the outside label of a product:
2,4,6-Trichlorobenzaldehyde
-
CAS No. 24473-00-5
- Cat. No. CS-W018721
- Purity≥97%
- MDL No.MFCD12024961
*For research and further manufacturing use only, not for direct human use.
Structure of 24473-00-5
Please choose your location and provide accurate information for you
| Size |
|
Price | Quantity | |||
|---|---|---|---|---|---|---|
|
* Please select Quantity before adding items. |
||||||
Recommended Products
General Information
- CAS No. 24473-00-5
- Cat. No. CS-W018721
- Purity ≥97%
- MDL No. MFCD12024961
- Storage 4°C, stored under nitrogen
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₇H₃Cl₃O
- Molecular Weight 209.46
- Synonym(s) ghl.PD_Mitscher_leg0.543
- SMILES ClC1=CC(Cl)=C(C=O)C(Cl)=C1
Description
2,4,6-Trichlorobenzaldehyde features a highly electron-deficient aromatic ring stabilized by three chlorine substituents, enabling efficient electrophilic coupling reactions. This bench-stable aldehyde integrates readily into synthetic sequences requiring strong inductive withdrawal, particularly in pharmaceutical intermediates and heterocyclic scaffold construction.
Application
2,4,6-Trichlorobenzaldehyde serves as a highly functionalized aromatic aldehyde enabling efficient access to substituted heterocycles and pharmaceutical intermediates. Its electron-deficient aryl ring enhances reactivity in nucleophilic addition and condensation reactions, while the three chlorine substituents provide orthogonal handles for further derivatization. Bench-stable and readily purified by recrystallization, it functions reliably in standard synthetic workflows including Ugi, Mannich, and Stetter reactions.
Synthesis
-
Route1
-
108-70-3 -
68-12-2
- ~91%
-
In-stock
24473-00-5
References
-
F. HOFFMANN-LA ROCHE AG; CHEN, Shaoqing; DE VICENTE FIDALGO, Javier; HAMILTON, Matthew Michael; HERMANN, Johannes Cornelius; KENNEDY-SMITH, Joshua; LI, Hongju; LOVEY, Allen John; LUCAS, Matthew C.; LUK, Kin-Chun Thomas; LYNCH, Stephen M.; O'YANG, Counde; PADILLA, Fernando; SCHOENFELD, Ryan Craig; SIDDURI, Achyutharao; SOTH, Michael; WANG, Ce; WOVKULICH, Peter Michael; ZHANG, Xiaohu Patent: WO2013/30138 A1, 2013 ; Location in patent: Page/Page column 250; 251 ;
-
-
Route2
-
In-stock
6575-05-9 - ~92%
-
In-stock
24473-00-5
References
-
ELI LILLY AND COMPANY Patent: WO2006/44454 A1, 2006 ; Location in patent: Page/Page column 74 ; WO 2006/044454 A1
-
-
Route3
-
In-stock
217479-60-2 - ~%
-
In-stock
24473-00-5
References
-
Banfi, Stefano; Cavazzini, Marco; Pozzi, Gianluca; Barkanova, Svetlana V.; Kaliya, Oleg L. Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 4 p. 871 - 877
-
Safety Information
Download SDS|
GHS Pictogram :
|
GHS No : GHS07
|
|
Signal Word : Warning
|
UN#: N/A
|
|
Class : N/A
|
Packing Group : N/A
|
|
Hazard Statements : H302-H315-H319-H335
|
|
|
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
|
|
Quality Control
Computational Chemistry Data
- TPSA 17.07
- LogP 3.4593
- H_Acceptors 1
- H_Donors 0
- Rotatable_Bonds 1
Similar Products
Other Classifications
Recently Viewed Products
Leave US a Message
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upload Pictures
|
|
Key Words
- 2,4,6-Trichlorobenzaldehyde sigma2,4,6-Trichlorobenzaldehyde manufacturer2,4,6-Trichlorobenzaldehyde price2,4,6-Trichlorobenzaldehyde structure2,4,6-Trichlorobenzaldehyde SDSbuy 2,4,6-Trichlorobenzaldehyde2,4,6-Trichlorobenzaldehyde supplier2,4,6-Trichlorobenzaldehyde uses2,4,6-Trichlorobenzaldehyde molecular weightprice of 2,4,6-Trichlorobenzaldehyde2,4,6-Trichlorobenzaldehyde chemical name formula of 2,4,6-Trichlorobenzaldehyde