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CS-W001157 4
Total: USD 88.00

(S)-3-(tert-Butyl)-4-(2,6-diphenoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole

  • CAS No. 2446042-08-4

  • Cat. No. CS-0092164
  • Molecule weight454.50
  • Purity≥97%
  • MDL No.MFCD32641150

*For research and further manufacturing use only, not for direct human use.

(S)-3-(tert-Butyl)-4-(2,6-diphenoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole|CS-0092164

Structure of 2446042-08-4

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General Information

  • CAS No. 2446042-08-4
  • Cat. No. CS-0092164
  • Purity ≥97%
  • MDL No. MFCD32641150
  • Storage 4°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₉H₂₇O₃P
  • Molecular Weight 454.50
  • Synonym(s) None
  • SMILES CC(C)(C)[P@]1C2=C(C3=C(OC4=CC=CC=C4)C=CC=C3OC5=CC=CC=C5)C=CC=C2OC1

Description

This chiral phosphole features a sterically shielded tert-butyl group and a diphenoxy-substituted aryl moiety, conferring enhanced stability and solubility. The oxaphosphole core enables efficient coupling in asymmetric synthesis, while the rigid framework supports precise stereocontrol in catalytic applications.

Application

(S)-3-(tert-Butyl)-4-(2,6-diphenoxyphenyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole serves as a stereochemically defined phosphole scaffold with enhanced bench stability and functional group tolerance. It enables efficient access to chiral phosphorus-containing building blocks via standard coupling reactions and functions as a versatile intermediate in the synthesis of phosphine ligands and bioactive heterocyclic architectures.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   27.69
  • LogP   8.1938
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   5

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