Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

5-Fluorobenzofuran

  • CAS No. 24410-59-1

  • Cat. No. CS-W022385
  • Purity≥96%
  • MDL No.MFCD08236757

*For research and further manufacturing use only, not for direct human use.

5-Fluorobenzofuran|CS-W022385

Structure of 24410-59-1

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 24410-59-1
  • Cat. No. CS-W022385
  • Purity ≥96%
  • MDL No. MFCD08236757
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₅FO
  • Molecular Weight 136.12
  • Synonym(s) 5-Fluorobenzo[b]furan
  • SMILES FC1=CC2=C(OC=C2)C=C1

Description

5-Fluorobenzofuran serves as a key heterocyclic scaffold in medicinal chemistry, offering enhanced metabolic stability and modulated electronic properties. This electron-deficient aryl moiety integrates readily into bioactive molecules, enabling efficient coupling reactions under standard conditions. Its fluorinated ring system enhances membrane permeability and binding affinity in target-directed compounds.

Application

5-Fluorobenzofuran serves as a valuable building block in medicinal chemistry, offering a fluorinated heterocyclic scaffold with enhanced metabolic stability and modulated lipophilicity. Its well-established reactivity enables palladium-catalyzed cross-coupling reactions, electrophilic substitutions, and direct functionalization at the 2- and 3-positions. The compound exhibits good bench stability and is compatible with standard purification methods, facilitating integration into complex molecule synthesis.

Synthesis

  • Route1
    • 1-(2,2-Diethoxyethoxy)-4-fluorobenzene|CS-0363318
      59769-37-8
    • ~44%
    • In-stock
      5-Fluorobenzofuran|CS-W022385
      24410-59-1

    References

    • Wyeth Patent: EP1147083 B1, 2004 ; Location in patent: Page 35 ; EP 1147083 B1
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 47, # 15 p. 3823 - 3842

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   13.14
  • LogP   2.5719
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 5-Fluorobenzofuran sigma5-Fluorobenzofuran manufacturer5-Fluorobenzofuran price5-Fluorobenzofuran structure5-Fluorobenzofuran SDSbuy 5-Fluorobenzofuran5-Fluorobenzofuran supplier5-Fluorobenzofuran uses5-Fluorobenzofuran molecular weightprice of 5-Fluorobenzofuran5-Fluorobenzofuran chemical name formula of 5-Fluorobenzofuran
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label