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CS-W001157 4
Total: USD 88.00

p-Fluorophenol

  • CAS No. 371-41-5

  • Cat. No. CS-W008731
  • Purity≥98%
  • MDL No.MFCD00002316

*For research and further manufacturing use only, not for direct human use.

p-Fluorophenol|CS-W008731

Structure of 371-41-5

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General Information

  • CAS No. 371-41-5
  • Cat. No. CS-W008731
  • Purity ≥98%
  • MDL No. MFCD00002316
  • Storage RT, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅FO
  • Molecular Weight 112.10
  • Synonym(s) Phenol, p-fluoro- (6CI,8CI); 4-Fluorophenol; Fluorophenoloffwhiteflakes
  • SMILES OC1=CC=C(F)C=C1

Application

p-Fluorophenol serves as a versatile building block in medicinal chemistry and materials science, enabling efficient access to fluorinated aromatic systems. Its moderate reactivity facilitates electrophilic substitution, nucleophilic displacement, and coupling reactions under standard conditions. The compound exhibits good bench stability, ease of purification, and compatibility with common functional groups, making it a reliable intermediate for synthesizing pharmaceuticals, agrochemicals, and specialty polymers.

Synthesis

  • Route1
    • null|null
      460-00-4
    • ~93%
    • In-stock
      p-Fluorophenol|CS-W008731
      371-41-5

    References

    • Chen, Junmin; Yuan, Tangjun; Hao, Wenyan; Cai, Mingzhong Catalysis Communications, 2011 , vol. 12, # 15 p. 1463 - 1465
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    References

    • Bartl; Dlabac; Protiva Collection of Czechoslovak Chemical Communications, 1980 , vol. 45, # 11 p. 3182 - 3189
  • Route3

    References

    • Gohain, Mukut; Du Plessis, Maretha; Van Tonder, Johannes H.; Bezuidenhoudt, Barend C.B. Tetrahedron Letters, 2014 , vol. 55, # 13 p. 2082 - 2084

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.5313
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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